Hi Gayle. Margaret cannot provide you with advice regarding your situation. This is best discussed with your physician. Thank you.

Hi Laura. Thank you for your comment. You should discuss this question with a health professional familiar with your medical history and knowledgeable in hormone replacement therapy.

Hi Valerie: Margaret is unable to provide you with medical advice on hormone use and encourages you to look into telemedicine options to consult with a specialist. You might want to checkout NutriChem: https://app.outsmartemr.com/online-booking/1768

I am 68 years old. I’ve had a compete fracture of my humerus and 2 years later a wrist fracture. Both required plates and pins to mend. I had a hysterectomy in 2018. I’ve had 3 annual injections of zolendronic acid (a bisphosphonate). I’ve done quite a bit of research on bio identical hormones and convinced my family doctor, against her wishes, to prescribe estradot and progesterone to me. I have been taking for them for 3 years as well.. I don’t feel that I am at my optimum and I wonder if it would be worth my while to get hormone testing? Until I read your article, I didn’t even know that it was available. As well I saw the article how eating prunes can prevent bone loss and even increase bone density. Because of Covid 19 I have not been able to get a bone density follow up scan. I don’t know if you can answer this but do you think that if I was to eat 100 mg of prunes daily, I could forego taking future injections of zolendronic acid? I’m sorry if I’ve put you on the spot, but I live in a small town in the interior of BC and we do not have doctors who specialize in hormones or osteoporosis. In fact, the community is critically short of doctors period.

Hi John, It is very kind of you to reach out on your wife’s behalf. I am sorry for her multiple vertebral fractures. It is well known that once someone has three or more vertebral fractures their risk of sustaining another vertebral fracture increases significantly.

I do not consider myself an alarmist but rather a realist. If your wife had low bone density and no vertebral fractures there would be time to look at exercise and possibly hormone replacement. However, since she has multiple vertebral fractures, she needs to work with an endocrinologist who can recommend a pharmaceutical such as Evinity or Prolia that will help her reduce her risk of future vertebral fractures. If you have not read our blog on Prolia I encourage you and your wife to do so. http://melioguide.com/?s=prolia

Ipriflavone is a synthetic isoflavone derivative. In ipriflavone showed promising results in initial animal studies, unfortunately not so in human studies. A 4-year study conducted in 4 centers in Europe investigated the effect of oral ipriflavone on the prevention of postmenopausal bone loss as well as assessing the safety profile of taking it long-term. The study group was composed of 234 postmenopausal women between the ages of 44-74 years. They took 200 mg of 3 times per day after 36 months of treatment, the annual percentage change from baseline in BMD of the lumbar spine for ipriflavone vs placebo, or in any of the other sites measured, did not differ significantly between groups. Prunes are more effective. http://melioguide.com/?s=prunes
I wish you both all the best.
Margaret

my wife is 63 with multiple vertebral fractures. She has not taken any medications and is contemplating Evista and Prolia. I have suggested she look at BHRT but she is reluctant due to a concern for weight gain etc. Do you think at age 63 (this month) she could consider BHRT. P.S. she is looking at Ipriflavone as well but I dont see any reference to this on your web pages.
Thank you

Hi Rima

We are in the process of rewriting the whole article and will be publishing the update in a few weeks. We do not use pharmaceutical intervention with our clients because we only offer physiotherapy services.